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负面情绪的影响,血清炎症因子,miR-155,以及来自大脑的神经营养因子

Qi Zhang¹, Yue Zhao², Guang-Yu Cheng³

¹Prevention and Treatment Center, First Affiliated Hospital Heilongjiang University of Chinese Medicine, Harbin 150040, Heilongjiang Province, China.

World journal of psychiatry

|February 20, 2025

概括

针与fluoxetine化相结合,显著改善了腹部手术患者的术后抑郁症. 这种综合方法提供了一个比单独使用药物更有效的治疗策略,通过调节炎症因素和抑郁症状.

科学领域:

综合医学是一个整体的医学.
神经科学是一个神经科学.
传统中国医药传统中国医药

背景情况:

手术后抑郁症是腹部手术患者的常见并发症,对康复产生负面影响.
针为治疗这种疾病提供了一个有前途的治疗选择.

研究的目的:

调查针在减轻腹部手术后的术后抑郁症的机制.
为了比较针结合fluoxetine化与单独使用fluoxetine化的疗效.

主要方法:

这是一项随机对照试验,涉及500名患有抑郁症的腹部手术患者.
患者接受了酸加针 (观察组) 或仅服用酸 (对照组).
评估结果包括抑郁症评分 (哈密尔顿抑郁症评分24),血清炎症因子 (TNF-α,IL-1β,IL-6),miR-155和BDNF水平.

主要成果:

观察组在6周后与对照组相比,在所有测量参数中均显著改善 (P < 0.05).
联合治疗在减少抑郁症状和调节炎症标志物方面表现出卓越的疗效.
针对调节miR-155和BDNF水平的作用需要进一步研究.

结论:

针与中国传统医学原则相一致,增强了手术后抑郁症的治疗效果.
针和fluoxetine化的组合提供了一个强大的策略,用于管理术后抑郁症和相关炎症.
针有效地改善抑郁症状,并调节关键的炎症血清标志物.

关键词:

腹部外科手术腹部外科手术抑郁症抑郁症抑郁症负面的情绪负面的情绪血清炎症因子是血清炎症因子.综合症差异化针针疗法这是一个微小的RNA-155 RNA.

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