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基于微生物合成和先进生物制造的三维等级纤维素结构.

Shan Liu1, Muxuan Yang1, Weinan Xu1

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科学领域:

  • 生物材料科学 生物材料科学
  • 聚合物科学 聚合物科学
  • 生物制造的生物制造

背景情况:

  • 纤维素是一种全球丰富的生物聚合物,其中细菌纤维素 (BC) 是由像*Komagataeibacter xylinus*这样的细菌产生的.
  • 制造3DBC结构是具有挑战性的,因为生物合成需要氧气,BC固有的结晶性和处理能力差.
  • 增材制造和生物制造的最新进展为创建层次的3D纤维素结构提供了新的策略.

研究的目的:

  • 批判性地检查对层次的3D纤维素结构的先进生物制造技术.
  • 探索添加剂制造与在现场微生物生物合成用于纤维素制造的整合.
  • 讨论基于BC和微生物生物合成的可持续生物复合材料.

主要方法:

  • 对将BC或纤维素生成细菌纳入3D打印原料的增材制造技术进行审查.
  • 使用纤维素生产细菌在活体油墨中的BC生物合成现场调查.
  • 分析将微生物生物合成与3D打印结合用于复杂结构制造的潜力.

主要成果:

  • 增材制造和生物制造为层次的3D纤维素结构提供了多功能方法.
  • 将细菌纳入活体油墨使复杂几何形状的BC生物合成能够在现场进行.
  • 可持续的生物复合材料可以使用BC和微生物生物合成来开发.

结论:

  • 将增材制造与微生物生物合成相结合,具有制造先进的3D纤维素结构的巨大潜力.
  • 在控制特定应用的BC生物合成和材料特性方面仍然存在挑战.
  • 未来的机遇在于开发组织工程,药物输送和先进复合材料的新应用.