双胞胎,单生儿和妊娠年龄相匹配的单生儿的早期儿童体重轨迹差异
Anna Booman1, Byron A Foster1,2, Kristin Lyon-Scott3
1School of Public Health, Oregon Health & Science University-Portland State University, Portland, OR, United States.
Preventive medicine reports
|February 20, 2025
概括
双胞胎婴儿体重迅速增加,但可能落后于单身婴儿. 男性双胞胎在6-12个月后赶上,而雌性双胞胎在15个月后赶上,这凸显了对双胞胎特定生长图的需求.
科学领域:
- 儿科 儿科 儿科
- 人类成长和发展 人类成长和发展
- 生物统计学 生物统计学
背景情况:
- 目前对美国双胞胎生长的理解依赖于过时的数据或非西班牙裔白人人口.
- 与单身双胞胎相比,双胞胎达到追赶成长的年龄仍然不清楚.
研究的目的:
- 在当代,多样化的美国队列中,对双胞胎和单身婴儿的规范体重轨迹进行描述.
- 为了将双胞胎生长模式与一般和妊娠年龄匹配的单独种群进行比较.
主要方法:
- 利用了来自PROMISE研究 (2005-2021) 的电子健康记录数据.
- 应用了Jenss模型来分析从出生到24个月的体重轨迹.
- 将716个双胞胎与40,075个单身双胞胎和7,160个妊娠年龄匹配的单身双胞胎进行了比较.
主要成果:
- 双胞胎的出生体重较低,但与单生婴儿相比,婴儿体重增加率较高.
- 男性双胞胎在6-12个月时与单生双胞胎达到平价.
- 雌性双胞胎在15个月时赶上了妊娠年龄的单身双胞胎,但在24个月时没有达到一般单身双胞胎队列.
结论:
- 单体生长图表可能不适合双胞胎种群.
- 这些发现表明需要双胞胎特定的增长图表.
- 需要进一步的研究来了解影响双胞胎生长轨迹的因素,并为指导方针提供信息.
相关概念视频
Nature and Nurture
20.3K
Many human characteristics, like height, are shaped by both nature—in other words, by our genes—and by nurture, or our environment. For example, chronic stress during childhood inhibits the production of growth hormones and consequently reduces bone growth and height. Scientists estimate that 70-90% of variation in height is due to genetic differences among individuals, and 10-30% of variation in height is due to differences in the environments that individuals experience,...
20.3K
Regression Toward the Mean
6.3K
Regression toward the mean (“RTM”) is a phenomenon in which extremely high or low values—for example, and individual’s blood pressure at a particular moment—appear closer to a group’s average upon remeasuring. Although this statistical peculiarity is the result of random error and chance, it has been problematic across various medical, scientific, financial and psychological applications. In particular, RTM, if not taken into account, can interfere when...
6.3K
Behavioral Genetics and Its Designs
318
Behavior genetics explores how genetic inheritance influences human behavior. It focuses on how genes, passed from parents to offspring, contribute to the development of behavioral traits and tendencies. This branch of genetics seeks to understand the complex interplay between inherited genetic factors and environmental influences in shaping our behaviors.
The primary methodologies used in behavior genetics include family studies, twin studies, and adoption studies, each providing unique...
The primary methodologies used in behavior genetics include family studies, twin studies, and adoption studies, each providing unique...
318
Heritability
189
Heritability is a statistical concept that measures the degree to which genetic differences among individuals contribute to trait variations within a population. It is a fundamental idea in genetics, often prone to misinterpretation. Heritability is expressed as a percentage, reflecting the proportion of variation in a specific trait across a population that can be linked to genetic differences. However, it's important to understand that heritability does not determine how "genetic"...
189
Longitudinal Studies
120
Longitudinal studies are also widely used in other medical and social science fields. For instance, in cardiovascular research, they can monitor patients' health over decades to identify risk factors for heart disease, such as high cholesterol or smoking, and evaluate the long-term effectiveness of preventive measures. Similarly, in mental health studies, researchers might follow individuals from adolescence into adulthood to understand the development and progression of conditions like...
120
Oogenesis
63.3K
In human women, oogenesis produces one mature egg cell or ovum for every precursor cell that enters meiosis. This process differs in two unique ways from the equivalent procedure of spermatogenesis in males. First, meiotic divisions during oogenesis are asymmetric, meaning that a large oocyte (containing most of the cytoplasm) and minor polar body are produced as a result of meiosis I, and again following meiosis II. Since only oocytes will go on to form embryos if fertilized, this unequal...
63.3K


