与艾滋病毒感染者和未感染者的mpox病例之间的流行病学和临床特征的比较分析 - - 中国,2023,
Yichen Jin1,2, Qianqian Qin1,2, Chao Li3,4
1National Center for AIDS/STD Control and Prevention, Chinese Center for Disease Control and Prevention, Beijing, China.
China CDC weekly
|February 20, 2025
概括
在2023年中国的mopox病例中,近一半与艾滋病毒同时感染. 症状相似,但艾滋病毒共感染影响了免疫缺陷和病毒抑制,突出显示了综合预防的需要.
科学领域:
- 流行病学 流行病学
- 传染性疾病 传染性疾病
- 公共卫生 公共卫生
背景情况:
- 麻疹 (原名麻疹) 和人类免疫缺陷病毒 (HIV) 是严重的公共卫生问题.
- 了解mopox和HIV之间的相互作用对于有效的控制策略至关重要.
研究的目的:
- 分析2023年中国mopox病例的流行病学特征和临床症状.
- 为了比较mopox病例与没有艾滋病毒共感染.
- 为协调预防和控制两种感染提供证据.
主要方法:
- 追溯分析了2023年在中国报告的1,712例确诊的mopox病例.
- 来自中国疾病控制和预防信息系统的数据.
- 使用t测试和千平方测试进行统计比较.
主要成果:
- 802 (46.8%) mpox病例是艾滋病毒感染者 (PWH).
- 在PWH和非HIV的mopox病例中,症状概况类似 (皮疹,发烧,淋巴腺病变).
- 同时感染艾滋病毒与较高的免疫缺陷和较低的艾滋病毒抑制有关.
结论:
- 感染艾滋病毒的男性mpox病例更有可能是与男性发生性关系的男性 (MSM),年长的男性和来自中部/西部地区的男性.
- 在艾滋病毒阳性和艾滋病毒阴性组之间没有观察到枢纽mopox症状的显著差异.
- 针对艾滋病毒和mpox的综合预防策略至关重要,特别是针对关键人群.
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