孕期体重增加对孕期不良结果的影响
Qingshan Yan1,2, Wenya Cai1,3, Yong Guo1
1Department of Health Care, Guangdong Women and Children Hospital, Guangzhou, China.
Frontiers in endocrinology
|February 20, 2025
概括
过度的妊娠体重增加 (GWG) 会增加妊娠高血压疾病的风险,以及对妊娠年龄大的婴儿的风险. 不足的GWG与妊娠糖尿病,妊娠年龄较小的婴儿和早产有关,强调需要监测GWG.
科学领域:
- 产科和妇科 产科和妇科
- 孕产妇和胎儿医学 孕产妇和胎儿医学
- 新生儿科学 新生儿科学
背景情况:
- 孕期体重增加 (GWG) 是影响怀孕结果的关键因素.
- 了解与不充分或过度GWG相关的特定风险对于母亲和婴儿健康至关重要.
- 以前的研究表明,GWG与各种不良怀孕和分娩结果之间存在相关性.
研究的目的:
- 调查母亲妊娠期体重增加 (GWG) 与母亲和新生儿的不良结果之间的联系.
- 量化与不同类别的GWG相关的特定不良结果的风险.
- 为怀孕期间管理GWG提供基于证据的建议.
主要方法:
- 追溯分析了9058例单独怀孕和新生儿的情况.
- 从2017年至2022年间的产前检查和分娩中收集的数据.
- 后勤回归分析,以评估GWG对妊娠高血压疾病 (HDP),妊娠糖尿病 (GDM),妊娠年龄大 (LGA) 婴儿,妊娠年龄小 (SGA) 婴儿和早产婴儿的影响.
主要成果:
- 过度的GWG被确定为HDP (OR=1.829) 和LGA婴儿 (OR=1.792) 的风险因素.
- 不足GWG与GDM (OR=2.203),SGA婴儿 (OR=1.474) 和早产 (早产/中产OR=3.326;晚产OR=1.715) 的风险增加有关.
- 发病率包括HDP的4.8%,GDM的22.3%,SGA的9.7%,LGA的9.9%,早产的联合出生率为5.6%.
结论:
- 孕期体重增加对母亲和婴儿的健康状况产生重大影响.
- 过度的GWG对高血压疾病和妊娠年龄大的婴儿构成风险.
- 不足的GWG与妊娠糖尿病,婴儿小于妊娠年龄和早产有关,强调需要适当的GWG管理.
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