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Updated: May 27, 2025

Characterization of Neuronal Lysosome Interactome with Proximity Labeling Proteomics
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同时对神经细胞类型的原始状态蛋白质组和转录组进行分析,使用近距离标记

Christina C Ramelow1,2,3, Eric B Dammer2,4, Hailian Xiao1,2

  • 1Department of Neurology, Emory University, Atlanta, GA.

bioRxiv : the preprint server for biology
|February 20, 2025
PubMed
概括

一种新的方法,即同时蛋白质和RNA-omics (SPARO),捕获细胞类型特定的蛋白质和转录蛋白质. 这促进了分子表型的发展,以了解发育,衰老和疾病.

关键词:
靠近标签的标签.星球细胞是星球细胞.mRNA-蛋白质对应性对应性微质细胞中的微质细胞神经元神经元的神经元蛋白质组学 蛋白质组学转录组学 转录组学是指转录组学.

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Ribosome Profiling

Ribosome profiling or ribo-sequencing is a deep sequencing technique that produces a snapshot of active translation in a cell. It selectively sequences the mRNAs protected by ribosomes to get an insight into a cell’s translation landscape at any given point in time.
Applications of ribosome profiling
Ribosome profiling has many applications, including in vivo monitoring of translation inside a particular organ or tissue type and quantifying new protein synthesis levels.
The technique...
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