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Updated: May 27, 2025

Analyzing Oxidative Stress in Murine Intestinal Organoids using Reactive Oxygen Species-Sensitive Fluorogenic Probe
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Analyzing Oxidative Stress in Murine Intestinal Organoids using Reactive Oxygen Species-Sensitive Fluorogenic Probe

Published on: September 17, 2021

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G蛋白结合受体OXER1是一种组织氧化还原传感器,对于肠道上皮质屏障完整性至关重要

Miklos Lengyel1, Yanan Ma1, Zaza Gelashvili1,2

  • 1Cell Biology Program, Memorial Sloan Kettering Cancer Center, New York, NY 10065, USA.

bioRxiv : the preprint server for biology
|February 20, 2025
PubMed
概括

反应性氧物种 (ROS) 适应是天生的免疫的关键. 这项研究揭示了5-oxo-eicosatetraenoic acid (5-KETE) 和它的受体OXER1通过诱导DNA修复机制来保护粘膜壁垒免受氧化应激.

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Assessment of Cellular Oxidation using a Subcellular Compartment-Specific Redox-Sensitive Green Fluorescent Protein06:10

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Peroxisomes

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G-Protein Gated Ion Channels

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