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Updated: May 27, 2025

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通过基于结构和基于基的建模,识别具有有利功效和药理动学的抗结核药物

Vedang Warapande, Fanwang Meng, Alexandra Bozan

    bioRxiv : the preprint server for biology
    |February 20, 2025
    PubMed
    概括

    研究人员开发了一种新的计算管道,以确定治疗Mycobacterium结核病感染的潜在候选药物. 这种方法成功提名了93种不同的抑制剂,其中12种显示出有希望的抗菌疗效和药物动力学特征.

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