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Updated: May 27, 2025

A Method to Study de novo Formation of Chromatin Domains
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A Method to Study de novo Formation of Chromatin Domains

Published on: August 23, 2019

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EZH2 的保存的 N-终端 SANT1 绑定域 (SBD) 调节 PRC2 活动

Agata L Patriotis, Yadira Soto-Feliciano, Douglas W Barrows

    bioRxiv : the preprint server for biology
    |February 20, 2025
    PubMed
    概括

    EZH2的SANT-绑定域 (SBD) 对多抑制复合体2 (PRC2) 甲基转移酶活性和基因调节至关重要. 它的完整性对于癌细胞增殖至关重要,特别是在EZH2突变淋巴瘤中.

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