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Updated: May 27, 2025

Monitoring GPCR-β-arrestin1/2 Interactions in Real Time Living Systems to Accelerate Drug Discovery
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Monitoring GPCR-β-arrestin1/2 Interactions in Real Time Living Systems to Accelerate Drug Discovery

Published on: June 28, 2019

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甲基氨酸受体/β-阿雷斯结合的结构多样性

Dagan C Marx, Alberto J Gonzalez-Hernandez, Kevin Huynh

    bioRxiv : the preprint server for biology
    |February 20, 2025
    PubMed
    概括

    这项研究揭示了多样化的β-arrestin (β-arr) 合与二次性甲基基因型谷氨酸受体 (mGluRs),揭示了新的2:1或2:2石化度和固体脱敏机制. 这些发现扩大了我们对G蛋白结合受体 (GPCR) 调节的理解.

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