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Updated: May 27, 2025

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VAMP8 缺乏症通过血小板重编程和增强的ECM稳定性减轻AngII诱导的腹腔大动脉动脉瘤形成

Shayan Mohammadmoradi, Elizabeth R Driehaus, Hammodah R Alfar

    bioRxiv : the preprint server for biology
    |February 20, 2025
    PubMed
    概括

    血管哨兵血小板及其VAMP8蛋白质是腹腔大动脉瘤 (AAA) 形成的关键. 抑制VAMP8-介导的血小板表细胞突变可以保护小鼠免受AAA的发展和破裂.

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