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Updated: May 27, 2025

Introduction to the Ultrasound Targeted Microbubble Destruction Technique
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Introduction to the Ultrasound Targeted Microbubble Destruction Technique

Published on: June 12, 2011

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使用超声波传递的点击反应进行增强的mRNA传递

Emilio Di Ianni, Jueun Jeon, Huiyu Hu

    bioRxiv : the preprint server for biology
    |February 20, 2025
    PubMed
    概括

    这项研究引入了一种超声波引导的策略,用于针对性核酸输送. 生物直角预定位增强了mRNA-脂质纳米粒子在肝外组织中的积累.

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    Capture and Identification of RNA-binding Proteins by Using Click Chemistry-assisted RNA-interactome Capture CARIC Strategy

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    Regulated mRNA Transport02:22

    Regulated mRNA Transport

    In eukaryotes, transcription and translation are compartmentalized; an mRNA is first synthesized in the nucleus and then selectively transported to the cytoplasm for protein synthesis. Before transport, a pre-mRNA undergoes several steps of post-transcriptional modifications including splicing, 5' capping, and the addition of a poly-adenine tail. Various proteins bind to the pre-mRNA during these modifications. The mRNA transport takes place with the help of multiple proteins playing...
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