人类和的皮层层次和深度的髓化
Monami Nishio1, Xingyu Liu1, Allyson P Mackey1
1Department of Psychology, School of Arts and Sciences, University of Pennsylvania, Philadelphia, Pennsylvania 19104, United States.
bioRxiv : the preprint server for biology
|February 20, 2025
概括
大脑髓化遵循了跨物种保存的"内外"模式. 人类表现出延长的髓化时间线,使得产后可塑性更大,并支持复杂的认知功能.
科学领域:
- 神经科学是一个神经科学.
- 发展生物学 发展生物学
- 比较解剖学的比较解剖学
背景情况:
- 髓化对于快速的神经通信和大脑可塑性至关重要.
- 皮层髓化模式在人类中已知,但保存与人类特异性特征尚不清楚.
- 灵长类人皮层的层状髓形成在很大程度上是未被探索的.
研究的目的:
- 为了比较人类和的依赖深度的髓化轨迹.
- 调查皮质髓化的保存和人类特异性特征.
- 了解扩展髓化在人类认知能力中的作用.
主要方法:
- 利用神经成像测量T1加权/T2加权比作为髓含量的代理.
- 系统地比较了人类和的皮层深度和区域的髓化模式.
- 分析了依赖深度和层次的髓化梯度.
主要成果:
- 确定了一个保存的"内外"髓化模式 (更深层更早成熟).
- 通过大脑皮层观察到髓化的层次梯度,从传感运动到关联区域.
- 与相比,人类表现出明显延长的髓化时间表.
结论:
- "内外"模式和髓化的层次梯度在物种之间得到保护.
- 在人类中,扩展的髓化支持长期的产后可塑性.
- 这种长期的可塑性可能是人类独特的感知和认知能力的基础.
相关概念视频
Nervous Tissue: Myelin
2.3K
The myelin sheath is a multilayered lipid and protein covering that insulates the axon of a neuron, enhancing the speed of nerve impulse conduction. Axons without this sheath are referred to as unmyelinated. Two types of neuroglia, Schwann cells in the peripheral nervous system (PNS) and oligodendrocytes in the central nervous system (CNS) are responsible for producing myelin sheaths.
Schwann cells begin to form myelin sheaths around axons during fetal development. They wrap around a small...
Schwann cells begin to form myelin sheaths around axons during fetal development. They wrap around a small...
2.3K
Organization of the Brain
693
The brain is an integral component of the nervous system and serves as the center for processing sensory inputs, making decisions, and directing bodily actions. This complex organ is organized into three primary sections: the hindbrain, midbrain, and forebrain, each responsible for a range of vital functions.
Hindbrain
The hindbrain, located at the base of the brain, plays a vital role in regulating automatic processes that sustain life. It includes the medulla oblongata, which is essential for...
Hindbrain
The hindbrain, located at the base of the brain, plays a vital role in regulating automatic processes that sustain life. It includes the medulla oblongata, which is essential for...
693


