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Updated: May 27, 2025

A High Resolution Method to Monitor Phosphorylation-dependent Activation of IRF3
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Published on: January 24, 2016

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干扰素β增强剂的基因调节逻辑包含多种选择性部署的转录因子协同作用模式

Allison Schiffman1, Zhang Cheng1, Diana Ourthiague1

  • 1Signaling Systems Laboratory, Department of Microbiology, Immunology and Molecular Genetics, and the Institute for Quantitative and Computational Biosciences (QCB), University of California Los Angeles, 611 Charles Young Drive, Los Angeles, CA 90095.

bioRxiv : the preprint server for biology
|February 20, 2025
PubMed
概括

I型干扰素 (IFNβ) 基因调节依赖于转录因子协同作用. 这项研究揭示了双干扰素调节因子 (IRF) 协同作用能够对病毒感染产生超敏感反应,而核因子kappa B (NFκB) 协同作用则驱动对细菌的反应.

关键词:
生物科学 生物科学布尔逻辑门的布尔逻辑门.在 NFκBB 的情况下.在Rig-I上.系统生物学 系统生物学这是一个TLR.基因调节电路的基因调节电路干扰素调节因子 (IRF) 是指干扰素的调节因子.干扰子-β的干扰.热力学状态组合模型的模型.

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