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Updated: May 27, 2025

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含有LRRC8A的离子通道通过WNK1/mTORC2-依赖机制促进质母细胞瘤的扩散

Antonio M Fidaleo1, Martin D Bach1, Shaina Orbeta1

  • 1Department of Neuroscience and Experimental Therapeutics, Albany Medical College, Albany, NY, USA.

bioRxiv : the preprint server for biology
|February 20, 2025
PubMed
概括

富含白的重复含有蛋白8A (LRRC8A) 通过调节水平和激活mTORC2信号来驱动质母细胞瘤的生长. 抑制LRRC8A或VRACs为这种致命的脑癌提供了潜在的治疗策略.

关键词:
癌症 癌症 癌症 癌症细胞生物学 细胞生物学分子生物学分子生物学

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