从童年到成年期的重复的时空大脑传播的发育变化
Kyoungseob Byeon1, Hyunjin Park2,3, Shinwon Park1
1Child Mind Institute, New York, NY, United States.
bioRxiv : the preprint server for biology
|February 20, 2025
概括
大脑活动模式从童年到成年期成熟,感官关联和任务积极/默认网络传播变得更长. 大脑动态中的这些发育转变支持认知发展.
科学领域:
- 神经科学是一个神经科学.
- 发育神经科学的发展神经科学.
- 认知神经科学 认知神经科学
背景情况:
- 大脑在从童年到青春期的发展过程中经历了显著的结构和功能变化.
- 神经发育遵循一个分层模式,在不同大脑区域的成熟度不同.
- 内在的时空大脑活动传播的成熟程度尚不清楚.
研究的目的:
- 研究从童年到成年早期的内在时空大脑活动传播的发育轨迹.
- 描述这些动态传播如何随着年龄的增长而变化,并与认知能力相关.
主要方法:
- 利用一种新的方法来分析大脑活动中的时间滞后动态传播.
- 检查了沿感官关联 (S-A),任务积极到默认网络 (TP-D) 和体机视觉 (SM-V) 轴的传播.
- 在两个独立的队列 (N=677) 中验证的结果.
主要成果:
- 大脑活动的传播在发育过程中向成年人的模式发展.
- 随着成熟,观察到长期发生的SA和TPD传播状态.
- 在发育过程中,SM-V传播状态的流行率下降.
- 上向下的SA传播随着年龄的增长而增加,并且预测认知得分比下向上的SA传播更好.
结论:
- 这项研究揭示了空间时空大脑活动动态的关键发育变化.
- 成熟包括长时间参与特定的网络传播状态 (S-A,TP-D).
- 上下S-A传播的年龄相关增加与认知功能有关,为年轻人大脑发育提供了洞察力.
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