怀孕前体重指数对产前的影响
Jing Mao1, Hanxiang Sun1, Qinxin Shen1
1Department of Obstetrics, Shanghai Key Laboratory of Maternal Fetal Medicine, Shanghai Institute of Maternal-Fetal Medicine and Gynecologic Oncology, Shanghai First Maternity and Infant Hospital, School of Medicine, Tongji University, Shanghai, China.
Frontiers in medicine
|February 20, 2025
概括
怀孕前体重不足与妊娠前风险降低有关,而超重和肥胖显著增加了中国妇女妊娠前和严重妊娠前的风险. 母亲年龄没有影响这些关联.
科学领域:
- 产科和妇科 产科和妇科
- 公共卫生 公共卫生
- 生殖健康 生殖健康
背景情况:
- 怀孕前体重指数 (BMI) 对中国人口孕前的影响尚未得到充分证实,原因是有限的大规模研究.
- 在全球范围内,孕前症对母亲和胎儿健康构成重大风险.
研究的目的:
- 调查妊娠前BMI类别与产前和严重产前风险之间的关联.
- 分析一个大型的中国队列中,根据母亲的年龄对这种关联的潜在修改.
主要方法:
- 一项回顾性研究分析了来自75,773名孕妇 (2016-2020) 的数据.
- 参与者被分为体重不足 (BMI <18.5 kg/m2),正常体重 (18.5-24 kg/m2),超重 (24-28 kg/m2) 和肥胖 (≥28 kg/m2) 的组.
- 使用后勤回归模型来评估几率比率 (ORs) 和95%置信区间 (CI),调整混因素并评估母亲年龄的影响.
主要成果:
- 体重较低的女性患子宫前风险降低 (OR=0.609) 和严重子宫前风险降低 (OR=0.720).
- 超重 (OR=2.152) 和肥胖 (OR=3.493) 的女性面临着明显更高的孕前的风险.
- 肥胖女性也有患重症孕前的风险增加 (OR=2.762).
- 这些风险并没有因母亲的年龄而显著改变.
结论:
- 怀孕前体重不足与妊娠前的风险较低有关.
- 超重和肥胖是中国妇女产前和严重产前的重要危险因素.
- 母亲年龄似乎不会改变怀孕前的BMI和孕前风险之间的关系.
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