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在DSD中女性化基因整形术的长期结果:生殖器形态,敏感性,性功能和满意度

Min Jeong Bag^1,2, Marlene Inacio³, Tânia Aparecida Sartori Sanchez Bachega³

¹Uropediatric Unit, Division of Urology, Hospital das Clínicas, Faculdade de Medicina, Universidade de São Paulo, São Paulo 05403-900, Brazil.

Journal of the Endocrine Society

|February 20, 2025

概括

性发育差异 (DSD) 患者的女性化生殖器官整形 (FG) 产生了令人满意的长期结果和高患者满意度. 大多数患者更喜欢儿童早期手术,并报告了积极的结果,对性功能没有显著影响.

科学领域:

泌尿器科泌尿器科泌尿器科泌尿器科
儿科手术儿科手术
内分泌学在内分泌学.

背景情况:

了解长期结果和患者满意度对于优化性发育差异 (DSD) 患者女性化生殖器造形 (FG) 治疗方案至关重要.
之前的研究集中在即时的外科结果上,不太重视长期的功能结果和患者报告的满意度.

研究的目的:

评估女性化生殖器造形术 (FG) 的长期形态和功能结果.
评估患者在性发育差异 (DSD) 患者队列中FG后的患者满意度.

主要方法:

从1965年到2016年进行了一项回顾性和横截面的队列研究,包括后续评估.
分析了60名经过FG的DSD患者,将他们分为先天性上腺增生 (CAH) 和非CAH组.
根据手术时的年龄和手术技术,评估了手术结果,生殖器敏感性,性功能和患者满意度.

主要成果:

91%的患者获得了正常的阴蒂大小,85%的患者有分离的围孔.
生殖器敏感性与对照组相似,在CAH患者中没有报告的整体性功能障碍.
89%的人更喜欢儿童手术,97%的人对手术结果感到满意.

结论:

性发育差异 (DSD) 患者的女性化基因整形 (FG) 在形态,功能和患者满意度方面表现出令人满意的长期结果.
在这个队列中,该程序对生殖器敏感性或性功能没有显著的负面影响.
大多数患者更喜欢早期的手术干预,这凸显了及时治疗在DSD管理中的重要性.

关键词:

出生性上腺增生症.性发展的差异性发展的差异.一个女人,一个女人,一个女人.人类的生殖器官.感觉值是指感觉值的值.性功能障碍性功能障碍性功能障碍

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