急性胰腺炎和慢性胰腺炎的急性胰腺炎的比较:一个回顾性队列研究
Tiago Bouça-Machado1,2, João Paulo Araújo Teixeira1,2, Paula Rebelo1
1Department of Surgery, São João University Hospital, Porto, Portugal.
European journal of gastroenterology & hepatology
|February 20, 2025
概括
急性慢性胰腺炎 (ACP) 患者的住院预后比急性胰腺炎 (AP) 患者更好,器官衰竭和重症监护室入院较少. 然而,ACP与像伪囊这样的局部并发症的风险更高有关.
科学领域:
- 胃肠病学 胃肠病学
- 内部医学 内部医学
- 临床研究 临床研究
背景情况:
- 急性至慢性胰腺炎 (ACP) 和急性胰腺炎 (AP) 呈现相似,但可能具有不同的风险概况.
- 有限的证据存在于ACP的具体特征和结果.
研究的目的:
- 为了比较患有ACP与AP的患者的临床特征和结果.
- 为了确定不同的风险概况和预测,为ACP.
主要方法:
- 在2017-2019年期间诊断出AP或ACP的成年患者的回顾性队列研究.
- 分析疾病严重程度,局部/全身并发症,器官衰竭,ICU入院和死亡率.
- 多变量逻辑回归用于比较ACP和AP组之间的结果.
主要成果:
- 与AP患者相比,ACP患者是年轻的男性,粉酶/脂酶水平较低.
- 在ACP和AP之间,中度或重度胰腺炎风险没有显著差异.
- 在ACP患者中,局部并发症 (伪囊) 的风险较高,但器官衰竭和ICU入院的风险较低.
结论:
- 与AP相比,ACP与更有利的住院预后有关.
- 结果与以前的观察结果一致,并在当代欧洲队列中得到验证.
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