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对癌症患者的疲劳进行心血管训练
Carina Wagner1, Moritz Ernst1, Nora Cryns1
1Cochrane Evidence Synthesis Unit Germany/UK, Cochrane Haematology, Institute of Public Health, Faculty of Medicine and University Hospital Cologne, University of Cologne, Cologne, Germany.
The Cochrane database of systematic reviews
|February 20, 2025
概括
在癌症治疗期间进行心血管训练可能会在短期内略有减少与癌症相关的疲劳 (CRF). 然而,关于长期影响和安全结果的证据仍然不确定,需要进一步研究.
科学领域:
- 在瘤学瘤学.
- 运动科学 运动科学
- 基于证据的医学基于证据的医学.
背景情况:
- 与癌症相关的疲劳 (CRF) 是影响癌症患者身体和精神健康的普遍和严重症状.
- 休息并不能缓解CRF,强调需要有效的干预措施.
- 练习在管理CRF方面表现有前途.
研究的目的:
- 评估心血管训练对癌症患者癌症相关疲劳 (CRF) 和生活质量 (QoL) 的影响.
- 根据抗癌治疗阶段 (前,期间或之后) 来评估心血管训练的影响.
- 为了检查与癌症患者的心血管训练相关的不良事件,焦虑和抑郁.
主要方法:
- 随机对照试验 (RCT) 的系统审查和元分析.
- 搜索了多个数据库,包括CENTRAL,MEDLINE,Embase,ClinicalTrials.gov和WHO ICTRP,直到2023年10月.
- 包括具有结构化的心血管训练 (≥5次,面对面指导) 和每组≥20名参与者的RCT.
主要成果:
- 治疗期间:中等确定性证据表明,心血管训练略有减少短期CRF,对短期QoL的影响很小.
- 关于对CRF和QoL以及对不良事件的中长期影响存在不确定性.
- 治疗后:非常低的确定性证据表明对短期和长期CRF,QoL和不良事件的影响的不确定性.
- 在治疗前没有确定对心血管训练的研究.
结论:
- 在癌症治疗期间的心血管训练为CRF提供了轻微的短期益处,对QoL的影响最小.
- 证据不足以确定长期的益处或风险,特别是在安全方面.
- 进一步的研究,包括正在进行的研究,对于澄清心血管训练在不同治疗阶段的作用和安全性至关重要.
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