社会孤立,抑郁症状和老年人的认知功能之间的关系:中国的一项纵向调解研究
Kerui Wang1, Yinuo Zhou1, Shaohui Su1
1Department of Epidemiology and Biostatistics, West China School of Public Health and West China Fourth Hospital, Sichuan University, No.17 Section 3, Renmin South Road, Chengdu, Sichuan, 610041, China.
Social psychiatry and psychiatric epidemiology
|February 20, 2025
概括
社会孤立对老年人的认知功能产生负面影响,抑郁症状部分介于这种影响. 相反,认知能力下降也预示着社会隔离的增加,尽管这种途径并非由抑郁症介导.
科学领域:
- 老年学是一门学科.
- 公共卫生 公共卫生
- 神经科学是一个神经科学.
背景情况:
- 社会孤立和认知障碍是影响老年人生活质量的重大公共卫生问题.
- 了解这些因素之间的动态相互作用对于开发有效的干预措施至关重要.
研究的目的:
- 研究老年人社会隔离与认知功能之间的双向关系.
- 检查抑郁症状在这种关系中的调解作用.
主要方法:
- 从中国健康和退休长度调查 (CHARLS) 中对5399名参与者的长度分析,分为三个波.
- 应用交叉滞后面板模型来评估社会隔离,抑郁症状和认知功能之间的时间关联.
主要成果:
- 较高的社会隔离预测了认知功能随后的下降,抑郁症状介导了37.5%的这种效应.
- 较低的认知功能预测了随后社会隔离的增加,这种关系不是由抑郁症状介导的.
结论:
- 在老年人中,社会隔离与认知功能之间存在双向关系.
- 抑郁症状部分介于从社会隔离到认知衰退的途径.
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