在俄勒冈州波特兰的娱乐性精神活性口香糖的定量分析
Matthew S Correia1,2, Mikayla J Gonzaga3, Courtney Temple1,2
1Oregon Poison Center, Portland, OR, USA.
Clinical toxicology (Philadelphia, Pa.)
|February 20, 2025
概括
精神活性口香糖标签通常是不准确的,产品声称含有Amanita muscaria,而不是含有素和其他胺. 许多口香糖含有未公开的精神活性化合物,构成安全风险.
科学领域:
- 法医化学 法医化学
- 药理学 药理学是指药理学的学科.
- 神经科学是一个神经科学.
背景情况:
- 俄勒冈州2020年109号和110号措施修改了精神活性物质法.
- 已经出现了包括在内的诺特罗普 (认知增强剂) 产品的商业市场.
- 有关这些商业可用的产品的安全性和准确标签存在担忧.
研究的目的:
- 为了评估商业无otropic 口香糖产品的标签准确性.
- 为了量化这些口香糖中的精神活性化合物含量.
- 为了确定产品声明与实际化学成分之间的差异.
主要方法:
- 在俄勒冈州波特兰的烟雾和vape商店购买了八种口香糖产品.
- 用液态色谱和四极点飞行时间质谱分析了样品.
- 进行了psilocybin,psilocin,Amanita muscaria衍生物和其他精神活性化合物的查.
主要成果:
- 两种声称是Amanita muscaria提取物的产品缺乏伊波丁酸和肌肉醇,但含有西洛辛和胺衍生物.
- 一个标有无西宾的产品对西宾的检测结果呈阳性.
- 在8种产品中,有7种含有psilocin;6种含有4-acetoxy-N,N,dimethyltryptamine;1种含有未公开的Δ9-tetrahydrocannabinol.
结论:
- 精神活性果糖的标签经常是不准确和不一致的.
- 检测到的精神活性化合物的度表明使用者可能会经历意想不到的副作用.
- 与阿曼尼塔菌提取物一起销售的产品往往含有血清胺特立巴胺,包括素.
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