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重复的Omicron感染克服T细胞免疫印记到原来的SARS-CoV-2

Yunfei Li1, Junyao Lu2, Liheng He1

  • 1Shanghai Institute of Immunology, Department of Microbiology and Immunology, Shanghai Jiao Tong University School of Medicine, Shanghai, China.

Journal of medical virology
|February 20, 2025
PubMed
概括

原始的SARS-CoV-2疫苗接种可以导致T细胞免疫印记对抗Omicron变种. 然而,重新感染Omicron亚型可以恢复T细胞免疫力,这表明需要针对SARS-CoV-2等高度突变的病原体的多价值疫苗.

关键词:
对于COVID-19疫苗的使用情况.奥米克朗病毒的再感染.S 蛋白特异IFN-γ释放水平.在SARS-CoV-2中.

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