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Updated: May 27, 2025

Efficient Construction of Drug-like Bispirocyclic Scaffolds Via Organocatalytic Cycloadditions of α-Imino γ-Lactones and Alkylidene Pyrazolones
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Efficient Construction of Drug-like Bispirocyclic Scaffolds Via Organocatalytic Cycloadditions of α-Imino γ-Lactones and Alkylidene Pyrazolones

Published on: February 7, 2019

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螺旋-C ((sp3) 原子转移:使用Ph2SCN2创建刚性三维结构

Qiu Sun1, Jan-Niklas Belting1, Julian Hauda1

  • 1Fakultät für Chemie und Chemische Biologie, Technische Universität Dortmund, Otto-Hahn-Str. 6, Dortmund, Germany.

Science (New York, N.Y.)
|February 20, 2025
PubMed
概括

研究人员开发了一种新的试剂,Ph2S=CN2,用于合成3D螺旋化合物. 这种方法有效地创建了螺旋中心,使得新的碳-碳和碳-原子结合无需金属催化剂.

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Author Spotlight: Experimental Approaches for the Synthesis of Low-Valent Metal-Organic Frameworks from Multitopic Phosphine Linkers07:14

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相关概念视频

Hybridization of Atomic Orbitals II03:35

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sp3d and sp3d 2 Hybridization
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Hybridization of Atomic Orbitals I

The mathematical expression known as the wave function, ψ, contains information about each orbital and the wavelike properties of electrons in an isolated atom. When atoms are bound together in a molecule, the wave functions combine to produce new mathematical descriptions that have different shapes. This process of combining the wave functions for atomic orbitals is called hybridization and is mathematically accomplished by the linear combination of atomic orbitals. The new orbitals that...
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Chirality at Nitrogen, Phosphorus, and Sulfur

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