超症对老年人的平衡和跌倒风险的影响:系统性审查
Zeinab Gasavi Nezhad1, Steven A Gard2, Mokhtar Arazpour3
1Neuromusculoskeletal Rehabilitation Research Center, University of Social Welfare and Rehabilitation Sciences, Tehran, IRAN; Student Research Committee, University of Social Welfare and Rehabilitation Sciences, Tehran, Iran; Department of Orthotics and Prosthetics, School of Rehabilitation, University of Social Welfare and Rehabilitation Sciences, Tehran, Iran.
Gait & posture
|February 20, 2025
概括
老年人的脊柱曲症Hyperkyphosis显著损害平衡,增加了跌倒的风险. 需要有针对性的干预措施来改善这种群体的稳定性并防止其下降.
科学领域:
- 老年学是一门学科.
- 整形外科 整形外科 整形外科
- 生物医学工程 生物医学工程
背景情况:
- 60岁以上的成年人中常见的脊椎曲症 - - 缩症,与平衡障碍和跌倒风险增加有关.
- 60岁以上的人中有多达40%受到影响,但由于研究不一致,对跌倒风险的确切影响尚不清楚.
- 这一系统性审查解决了对老年人超症-平衡关系的清晰度的需求.
研究的目的:
- 系统地审查和综合现有的研究,对超症和老年人的平衡之间的关系.
- 为了澄清超症对平衡障碍和跌倒风险的影响.
- 确定对这一群体有针对性的干预措施的需要.
主要方法:
- 按照PRISMA 2020指南进行系统审查,并注册在PROSPERO.
- 包括观察性研究 (横截面,队列,病例对照) 涉及老年人 (≥60岁) 患有超症.
- 在主要数据库 (PubMed,科学网,Scopus,CINAHL,Cochrane图书馆) 进行全面的文献搜索,并使用STROBE检查清单进行质量评估.
主要成果:
- 包括19项涉及60岁以上成年人的研究,表现出不同的方法质量.
- 通过像科布角度这样的方法来测量的超症始终与静态和动态平衡 (例如,TUG,BBS) 的显著损害有关.
- 报告的跌倒率在24%至64%之间,许多跌倒导致受伤.
结论:
- 超症显著损害平衡,并提高老年人跌倒的风险.
- 降低姿势稳定性和较高的跌倒发病率直接与超症有关.
- 有针对性的干预措施对于增强稳定性,预防跌倒和改善生活质量至关重要.
相关概念视频
Bone Disorders
Aging and its effect on bone remodeling is the most common cause of bone disorders. In young and healthy people, bone deposition and resorption happen at an equal rate to maintain optimal bone health.
Bone deposition is also affected by the levels of sex hormones like estrogen and testosterone that promote osteoblast activity and bone matrix synthesis. When the level of these hormones decreases due to aging, it causes a reduction in bone deposition. As a result, bone resorption by osteoclasts...
Bone deposition is also affected by the levels of sex hormones like estrogen and testosterone that promote osteoblast activity and bone matrix synthesis. When the level of these hormones decreases due to aging, it causes a reduction in bone deposition. As a result, bone resorption by osteoclasts...
Pharmacokinetics in Geriatric Patients: Effect of Age on Drug Distribution
Drug distribution in the human body is influenced by several factors, including plasma protein concentration, body composition, blood flow, tissue-protein concentration, and tissue fluid pH. Among these, changes in plasma protein concentration and body composition due to aging significantly affect how drugs are distributed within the body. Specifically, aging is associated with a decrease in albumin levels by about 10% and an increase in α1-acid glycoprotein levels. These alterations are not...
Pharmacokinetics in Geriatric Patients: Effect of Age on Drug Metabolism
Geriatric patients show significant variation in how their bodies process medications, which can change how effective and safe treatments are. The liver is the primary organ where drug metabolism occurs, involving two main types of chemical reactions: phase I and II. Phase I metabolism is driven by the cytochrome P450 enzyme system, which includes key types such as CYP3A, CYP2D6, and CYP2C9. Research indicates that while aging doesn't notably alter the levels or activity of these enzymes, it...
Pharmacodynamics in Geriatric Patients: Effects of Age
Age-related pharmacokinetic changes are extensively documented, but understanding age-related pharmacodynamic alterations is relatively limited. This knowledge gap can be partly attributed to the complexity of developing appropriate measures of drug responses compared to bioanalytical methods for determining drug concentrations.Most information regarding age-related differences in human pharmacodynamics originates from cross-sectional studies. However, these studies assume that observed mean...


