在儿科重症监护室输血红细胞的频率和预测因素:一项前性观察性研究
Surya Kant Tiwari1, Jomol Rajesh2, Neethu Mariya Mathew2
1College of Nursing, All India Institute of Medical Sciences, Raebareli, Uttar Pradesh, 229405, India.
在儿科重症监护室 (PICU) 中,大约三分之一的重症儿童接受了红细胞 (RBC) 输血. 较高的入院血红蛋白水平降低了输血几率,而败血症则增加了输血几率,为资源有限的环境中的输血实践提供了信息.
科学领域:
- 儿科重症监护医学 儿科重症监护医学
- 输血医学 输血医学
- 血液学 血液学 血液学
背景情况:
- 红细胞 (RBC) 输血是儿科重症监护室 (PICU) 贫血治疗的基石治疗.
- 人们仍然担心红细胞输血对重症儿童的安全性和必要性.
- 了解输血模式至关重要,特别是在低收入和中等收入国家 (LMIC).
研究的目的:
- 为了确定重症儿童红细胞输血的频率.
- 在这个人群中确定红细胞输血的预测因子.
- 提供与LMICs输血实践相关的见解.
主要方法:
- 一项前性观察性研究在单中心PICU中进行.
- 在2021年1月至9月期间,有104名重症儿童被录取.
- 收集的数据包括人口统计,临床因素和结果;后勤回归确定了输血预测因素.
主要成果:
- 35.6%的患者 (37/104) 接受了红细胞输血.
- 输血患者的镇静率更高,使用血管活性剂,PICU停留时间更长,VAP,休克,呼吸衰竭和MODS的发病率增加.
- 入院血红蛋白>10 g/dL降低了红细胞输血几率 (OR=0.57),而败血症增加了几率 (OR=3.24).
结论:
- 在PICU中,大约三分之一的重症儿童接受了红细胞输血.
- 入院时的血红蛋白水平和败血症显著影响了输血的可能性.
- 调查结果强调,需要在LMIC中制定明智的输血策略,以优化结果和资源使用.
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Published on: September 6, 2017
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