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Updated: May 27, 2025

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发表后的同行评审和COVID-19试验中的方法和报告问题的识别:一种定性研究
Mauricia Davidson1, Christoffer Bruun Korfitsen2,3, Carolina Riveros4,5,6
1Université Paris Cité and Université Sorbonne Paris Nord, Inserm, INRAE, Centre for Research in Epidemiology and Statistics (CRESS), Paris, Île-de-France, France mauricia.davidson@gmail.com.
BMJ evidence-based medicine
|February 20, 2025
概括
系统审查员在大多数COVID-19随机对照试验 (RCT) 中发现了易于解决的问题. 出版后的同行评审在识别这些方法和报告问题的有效性有限.
科学领域:
- 临床试验 临床试验
- 系统审查是系统的审查.
- 科学出版科学出版
背景情况:
- 在COVID-19试验中的方法和报告问题可能会影响研究完整性.
- 系统审查和出版后的同行评审对于识别这些问题至关重要.
研究的目的:
- 评估系统审查者和出版后同行评审在COVID-19试验中发现容易解决的问题的程度.
- 评估不同同行评审机制在提高手稿质量的有效性.
主要方法:
- 分析COVID-NMA生活系统审查数据的定性研究.
- 包括对系统审查员偏见风险和结果报告偏见的评估.
- 在PubPeer和预印服务器 (medRxiv,研究广场,SSRN) 上搜索评论数据,截至2023年11月.
主要成果:
- 系统审查人员在500个符合条件的COVID-19RCT中发现了89%的问题,其中78%是容易解决的.
- 常见问题包括不完整的报告 (49%) 和报告结果的选择 (52%).
- 发表后的同行评审在9%的RCT中发现了易于解决的问题,有效性有限.
结论:
- 系统审查者有效地识别COVID-19RCT中容易纠正的问题.
- 缺乏作者反机制意味着错失了改进手稿的机会.
- 出版后的同行评审,尽管有反循环,但在识别这些问题方面表现出有限的有效性.
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