[影响术后嗅觉功能的因素分析,慢性鼻炎与鼻的患者]
1Department of Otolaryngology Head and Neck Surgery, the First Affiliated Hospital of Chongqing Medical University, Chongqing 400016, China.
概括
透视鼻手术改善了56%的患有鼻息息肉 (CRSwNP) 患者的慢性鼻炎的嗅觉功能. 诸如过敏性鼻炎和息肉严重程度等因素影响恢复,有助于预测模型.
科学领域:
- 耳鼻喉科 耳鼻喉科 耳鼻喉科
- 外科手术的结果
- 嗅觉功能障碍研究 嗅觉功能障碍研究
背景情况:
- 长期带鼻息肉的鼻鼻炎 (CRSwNP) 经常导致嗅觉功能障碍.
- 内镜外科手术 (ESS) 是主要的治疗方法,但嗅觉恢复率和影响因素需要进一步阐明.
研究的目的:
- 在CRSwNP患者中分析ESS后的嗅觉功能恢复.
- 为了确定CRSwNP手术后嗅觉改善的预测因素.
主要方法:
- 追溯分析277名CRSwNP患者的嗅觉功能障碍,接受ESS.
- 手术前的评估包括CT扫描,多得分和乙素/IL-6水平.
- 使用宾夕法尼亚大学气味识别测试 (UPSIT) 评估的嗅觉功能,手术前后.
主要成果:
- 56%的患者在ESS后经历了嗅觉功能的改善.
- 改善嗅觉的独立预测因素包括过敏性鼻炎,更长的功能障碍持续时间,更高的CT嗅觉区域得分,更高的隆德-肯尼迪得分,嗅觉裂多,高质细胞和IL-6水平.
- 更高的内镜聚得分与更低的改善率有关.
结论:
- 一些因素,包括同时发生的过敏性鼻炎,疾病严重程度和炎症标志物,在CRSwNP患者中显著影响ESS后的嗅觉恢复.
- 一个经过验证的诺莫格拉姆模型在预测术后嗅觉功能方面表现出良好的有效性,有助于临床决策.
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