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Updated: May 27, 2025

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基于活动的传感显示,高性铜通过肝 ALDH1A1 枯竭促进肝脏衰老

Zhenxiang Zhao1,2, Melissa Y Lucero1,2, Shengzhang Su1,2

  • 1Department of Chemistry, University of Illinois Urbana-Champaign, Urbana, IL, USA.

Nature communications
|February 20, 2025
PubMed
概括

衰老会增加肝脏中的铜活性,降低保护性酶. 铜化疗法可以恢复平衡并对抗衰老的影响,提供一种潜在的治疗策略.

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Aging01:26

Aging

Aging is a complex biological phenomenon influenced by various processes that affect cellular and systemic functions. Several prominent theories attempt to explain its mechanisms, highlighting cellular limitations, oxidative damage, and hormonal changes as central factors in aging.
Cellular Clock Theory
The cellular clock theory posits that the human lifespan is closely tied to the finite capacity of cells to divide, a phenomenon governed by telomeres, which are protective caps at the ends of...
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