低全球变暖潜力的吸入器处方趋势:2018-2024年英国范围内的队列比较
Simon M Barry1,2, Gareth R Davies3, Julian Forton4,5
1Respiratory Medicine, Cardiff and Vale UHB, Cardiff, UK. BarryS5@cardiff.ac.uk.
NPJ primary care respiratory medicine
|February 20, 2025
概括
在英国,对低全球变暖潜力 (GWP) 吸入器的处方有所不同. 威尔士的低GWP吸入器使用量大幅增加,减少了碳排放,与其他地区不同.
科学领域:
- 环境科学 环境科学
- 公共卫生 公共卫生
- 药理学 药理学是指药理学的学科.
背景情况:
- 吸入器对于呼吸系统疾病管理至关重要.
- 传统的计量剂量吸入器 (MDIs) 通常使用具有高全球变暖潜力 (GWP) 的碳水化合物.
- 过渡到低GWP替代品是医疗保健中一个关键的环境可持续性目标.
研究的目的:
- 分析整个英国初级保健中处方低GWP吸入器的趋势.
- 为了比较2018年至2024年在英格兰,苏格兰,威尔士和北爱尔兰的低GWP吸入器的采用率.
- 评估相关的环境影响,特别是二氧化碳当量 (CO2e) 的节约.
主要方法:
- 对国家处方数据的回顾性队列分析.
- 包括来自英格兰,苏格兰,威尔士和北爱尔兰的初级保健数据.
- 分析的时间段:2018年至2024年.
主要成果:
- 在英格兰,低GWP吸入器处方的变化很小.
- 在苏格兰 (36.6%至31.0%) 和北爱尔兰 (36.7%至33.2%) 观察到减少.
- 在威尔士显著增加 (30.8%至41.1%),同时高GWP吸入器使用量下降. 威尔士实现了20303二氧化碳的节约.
结论:
- 低GWP选项的吸入器处方趋势在英国各国有很大的差异.
- 威尔士证明了向低GWP吸入器的成功过渡,有助于实现环境目标.
- 可能需要进一步的干预,以促进英国其他地区的低GWP吸入器的采用.
相关概念视频
Inhaled Medications
219
Inhaled medications are crucial for managing chronic obstructive pulmonary disease (COPD) and asthma. They are essential for effective treatment and control, ensuring optimal respiratory health and well-being. Inhaled medication delivers drugs directly to the lungs, providing a rapid onset of action and reducing systemic side effects compared to oral or injectable medications. Three primary types of inhalation devices are used to administer these medications: nebulizers, metered-dose inhalers...
219
Drugs Used in Lower Respiratory Disorders: Overview
341
Lower respiratory tract disorders present challenges that often require skilled and nuanced approaches for effective management. Common ailments, such as asthma and chronic obstructive pulmonary disease (COPD), have prompted the development of intricate treatment strategies involving bronchodilators and anti-inflammatory drugs, each tailored to ease breathing and revitalize the lungs.
Bronchodilators, the first step of respiration enhancement, come in various forms, each with its own mechanism...
Bronchodilators, the first step of respiration enhancement, come in various forms, each with its own mechanism...
341
Asthma-IV: Diagnostic and Management
2.5K
The diagnosis and management of asthma are comprehensive, encompassing clinical assessments, lung function tests, and pharmacological interventions. Here's an overview:
Clinical Assessment for Asthma:
This is the first step in diagnosing and managing asthma. It includes:
Clinical Assessment for Asthma:
This is the first step in diagnosing and managing asthma. It includes:
2.5K
Antiasthma Drugs: Inhaled Corticosteroids and Glucocorticoids
212
Inhaled corticosteroids (ICS) are anti-inflammatory drugs used primarily in treating persistent asthma and providing long-term maintenance. They target the bronchial mucosa, the lining of the airways, to control inflammation, a critical factor in asthma progression and exacerbation.
ICS work through a multifaceted mechanism of action. They suppress the inflammatory response caused by the proliferation of TH cells. They also reduce the transcription of the IL-2 gene, which is involved in the...
ICS work through a multifaceted mechanism of action. They suppress the inflammatory response caused by the proliferation of TH cells. They also reduce the transcription of the IL-2 gene, which is involved in the...
212
COPD: Management Using Bronchodilators and Corticosteroids
172
Chronic obstructive pulmonary isease (COPD) involves a group of progressive lung disorders characterized by persistent airflow limitation and chronic respiratory symptoms. Asthma-COPD Overlap Syndrome (ACOS), encompassing features of both asthma and Chronic obstructive pulmonary disease (COPD), is a group of progressive lung disorders that includes chronic bronchitis, emphysema, and refractory (non-reversible) asthma. ACOS leads to complex clinical presentations that combine the inflammatory...
172
Inhalational Anesthetics: Overview
165
Inhalation anesthetics are drugs that induce general anesthesia upon inhalation. They work by increasing the sensitivity of GABAA receptors or inhibiting NMDA receptors, leading to a decrease in central nervous system activity. The depth of anesthesia can be rapidly adjusted by changing the concentration of the inhaled gas. Some common examples of inhalational anesthetics include volatile liquids like isoflurane, desflurane, sevoflurane and gases like xenon and nitrous oxide. Isoflurane, a...
165


