在新生儿出生与先天性胃肠道异常的一般运动评估:一个单位,回顾性研究研究
Lisa Soumekh1, Samantha Bell1, Sandra L Espinosa1
1Department of Pediatrics, David Geffen School of Medicine, University of California Los Angeles, Los Angeles, CA, USA.
概括
患有胃肠道异常的婴儿经常表现出异常的总体运动,类似于出生时极低体重的婴儿. 这些群体之间具体的扭动运动模式有很大的不同,这表明了潜在的运动缺陷风险.
科学领域:
- 新生儿神经学 新生儿神经学
- 发育儿科 发育儿科
- 胃肠病学 胃肠病学
背景情况:
- 一般运动 (GMs) 对于评估婴儿的神经发育至关重要.
- 先天性胃肠道 (GI) 异常会影响神经发育结果.
- 众所周知,极低出生体重 (ELBW) 的婴儿患运动障碍的风险更高.
研究的目的:
- 对于具有先天性肠胃异常的新生儿的一般运动的特征.
- 为了将这些运动与ELBW婴儿的运动进行比较.
- 为了确定潜在的早期生物标志物对于运动缺陷.
主要方法:
- 追溯性,单个地点的研究设计.
- 包括两个组:新生儿有肠胃异常和ELBW婴儿 (出生体重<1公斤).
- 主要结果指标:一般运动评估 (GMA).
主要成果:
- 分析了96名婴儿 (51个GI组,45个ELBW组).
- 在不同组之间观察到异常扭曲 (61%vs. 59%) 和不安动作 (20%vs. 36%) 的比较率.
- 在扭曲运动质量方面发现了显著的差异:GI组的100%糟糕的曲目,而ELBW组的50%糟糕的曲目和50%紧张的同步曲目 (p < 0.001).
结论:
- 患有先天性消化道异常的新生儿存在异常一般运动的显著风险.
- 异常的动动作可能是这种人群未来运动缺陷的早期指标.
- 了解转基因模式可以帮助早期检测和干预运动障碍.
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