[18F]FDG PET/CT在持久性危急疾病中识别感染和炎症焦点
Bram van Leer1,2,3, Jelle L G Haitsma Mulier4,5, Cornelis P van Stee6,7
1Department of Critical Care, University Medical Centre Groningen, University of Groningen, Groningen, The Netherlands. b.van.leer@umcg.nl.
Annals of intensive care
|February 20, 2025
概括
[F]FDG PET/CT扫描在重症患者中发现了新的感染和炎症,往往导致治疗变化. 这种成像技术在治疗持续性严重疾病方面表现有前途.
科学领域:
- 医疗成像医学成像
- 核医学就是核医学.
- 密集护理医学 密集护理医学
背景情况:
- 危急病患者经常由于二次感染和全身炎症而患有持续性器官衰竭.
- 18FDG PET/CT可以可视化感染和炎症过程.
研究的目的:
- 评估FDG PET/CT在持久性严重疾病中检测感染/炎症焦点的能力.
- 评估[18F]FDG PET/CT对患者管理的影响.
主要方法:
- 47名持久性严重疾病的ICU患者 (2017-2024) 的回顾性双中心研究.
- [18F]FDG PET/CT 进行在 ICU 入院后 ≥10 天.
- 分析PET/CT报告和诊断和治疗变化的临床记录.
主要成果:
- 在91%的患者中,FDG PET/CT检测到感染/炎症焦点 (34%之前未知).
- 扫描是在诊断工作后期进行的 (中位数为7个先前程序).
- 55%的患者在扫描后48小时内改变了治疗方法.
结论:
- FDG PET/CT对于在持久性严重疾病中识别新的传染性/炎症焦点非常有价值.
- 发现往往导致治疗调整.
- 需要进一步的研究来确定其在管理这些复杂患者中的作用.
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