在透析患者中艾滋病毒的全球流行病学:系统性审查和元分析
Shahad Saif Khandker1, Safrin Jahan2, Adiba Ayesha Khan3
1Department of Biochemistry and Molecular Biology, Gono Bishwabidyalay, Dhaka, 1344, Bangladesh. shahadsaifkhandker@gmail.com.
International urology and nephrology
|February 20, 2025
概括
在透析患者中,人类免疫缺陷病毒 (HIV) 的全球流行率为0.8%. 在非洲和北美观察到更高的比率,可能是由于意识和医疗保健差异.
科学领域:
- 流行病学 流行病学
- 公共卫生 公共卫生
- 传染性疾病 传染性疾病
背景情况:
- 透析患者的艾滋病毒感染是全球重要的健康问题.
- 透析患者由于免疫系统受损和治疗期间潜在的暴露,风险增加.
- 了解全球流行病学对于有针对性的预防和控制战略至关重要.
研究的目的:
- 确定透析患者中艾滋病毒感染的全球流行病学状况.
- 为了识别不同大陆的艾滋病毒流行率的变化.
- 为这个弱势群体提供公共卫生干预信息.
主要方法:
- 进行了系统性审查和元分析.
- 在Google Scholar,PubMed和ScienceDirect数据库中进行了搜索.
- 分析中包括了15项符合条件的研究.
主要成果:
- 在透析患者中,艾滋病毒的全球综合流行率为0.8% (95%CI为0.4至1.2).
- 在研究中观察到显著的异质性 (95%).
- 患病率因大陆而异:非洲 (21.1%) 和北美 (19.3%) 与欧洲 (0.3%),南美 (0.7%) 和亚洲 (0.7%) 相比,患病率更高.
结论:
- 在透析患者中,艾滋病毒发病率存在显著的地理差异.
- 缺乏意识,医疗保健不足和感染控制方面的漏洞等因素可能导致某些地区的发病率更高.
- 全球范围内建议加强预防实践,开展公众宣传活动,改善医疗保健系统.
更多相关视频
13:58Amplifying and Quantifying HIV-1 RNA in HIV Infected Individuals with Viral Loads Below the Limit of Detection by Standard Clinical Assays
Published on: September 26, 2011
31.5K
13:50Sequencing of Bacterial Microflora in Peripheral Blood: our Experience with HIV-infected Patients
Published on: June 11, 2011
12.2K
相关概念视频
01:27Dialysis
278
Renal failure occurs when the kidneys lose their ability to filter waste products from the blood effectively. It can be classified into two types: acute renal failure (ARF) and chronic renal failure (CRF).
Acute kidney injury develops suddenly and can be caused by pre-renal causes (e.g., hypovolemia, shock), intrinsic renal causes (e.g., acute tubular necrosis), or post-renal causes (e.g., urinary obstruction). In contrast, chronic renal failure progresses gradually over time and is often...
Acute kidney injury develops suddenly and can be caused by pre-renal causes (e.g., hypovolemia, shock), intrinsic renal causes (e.g., acute tubular necrosis), or post-renal causes (e.g., urinary obstruction). In contrast, chronic renal failure progresses gradually over time and is often...
278
01:10Retrovirus Life Cycles
45.8K
Retroviruses have a single-stranded RNA genome that undergoes a special form of replication. Once the retrovirus has entered the host cell, an enzyme called reverse transcriptase synthesizes double-stranded DNA from the retroviral RNA genome. This DNA copy of the genome is then integrated into the host’s genome inside the nucleus via an enzyme called integrase. Consequently, the retroviral genome is transcribed into RNA whenever the host’s genome is transcribed, allowing the...
45.8K
01:29Pulmonary Tuberculosis I
227
Tuberculosis, often called TB, is a contagious illness primarily caused by Mycobacterium tuberculosis. It mainly affects the lung parenchyma but can also impact other body parts.
Causative Organism
The primary infectious agent causing tuberculosis is Mycobacterium tuberculosis, a slow-growing, acid-fast, aerobic rod that exhibits sensitivity to heat and ultraviolet light. Instances of Mycobacterium bovis and Mycobacterium avium contributing to the development of TB infection are rare.
Mode of...
Causative Organism
The primary infectious agent causing tuberculosis is Mycobacterium tuberculosis, a slow-growing, acid-fast, aerobic rod that exhibits sensitivity to heat and ultraviolet light. Instances of Mycobacterium bovis and Mycobacterium avium contributing to the development of TB infection are rare.
Mode of...
227
01:26Sexually Transmitted Infections
290
Sexually transmitted infections (STIs) are diseases transmitted primarily through unsafe sexual interactions. Bacteria, viruses, or parasites cause them and can result in severe health complications if untreated.ChlamydiaThe bacterium Chlamydia trachomatis is responsible for the disease Chlamydia, the most common STI in the United States. This peculiar pathogen requires human cells to reproduce, residing intracellularly. The initial infection often goes unnoticed because it typically does not...
290