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Updated: May 27, 2025

Isolation of Intermediate Filament Proteins from Multiple Mouse Tissues to Study Aging-associated Post-translational Modifications
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Published on: May 18, 2017

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在老化过程中,STAT1的β-hydroxybutyrylation和O-GlcNAc修改调节了抗病毒防御

Yibo Zuo1,2, Qin Wang1, Wanying Tian2

  • 1Department of Laboratory Medicine, Institute of Laboratory Medicine, Sichuan Provincial People's Hospital, School of Medicine, University of Electronic Science and Technology of China, Chengdu, 611731, Sichuan, China.

Cellular & molecular immunology
|February 20, 2025
PubMed
概括

衰老通过促进STAT1β-基基化 (Kbhb) 来削弱抗病毒防御. 氧坎普托西因和果糖通过调节蛋白质修饰,显示出恢复老年人免疫功能的潜力.

关键词:
衰老的衰老 衰老的衰老这就是O-GLcNAcc.美国国家统计局 (STAT1)这是一种β-hydroxybutyrylation.

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