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Updated: May 5, 2026

Retroviral Transduction of T-cell Receptors in Mouse T-cells
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重置:一种与TCR合的抗原受体,具有优越的准灵敏度和可逆药物调节的抗瘤活性

Jardin Leleux1, Jillian Rosenberg2, Olmo Sonzogni1

  • 12seventy bio, Cambridge, MA 02124, USA.

Molecular therapy : the journal of the American Society of Gene Therapy
|February 21, 2025
PubMed
概括

研究人员开发了RESET-T细胞,这是一种结合抗原向与小分子控制的新疗法. 这些工程T细胞显示出更好的安全性和有效性,可能增强癌症免疫疗法.

关键词:
T细胞受体受体的 T 细胞受体.支持TCR的化学受体受体.仿制性抗原受体的仿制性抗原受体药物受监管的药物受监管的药物药理学控制 药理学控制 药理学控制这种药物是拉帕米辛 (Rapamycin).

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