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Updated: May 27, 2025

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一种用于研究Atractylodes LanceaDC的抗癌潜力和控制ROS介导的亡对前列腺癌细胞的药理信息方法

Chi-Hoon Ahn1, Ji Soo Myong2, Kazi Rejvee Ahmed1

  • 1College of Korean Medicine, Kyung Hee University, Seoul, Republic of Korea.

Frontiers in oncology
|February 21, 2025
PubMed
概括

阿特拉提洛德斯兰切亚 (ALD) 通过诱导ROS介导的亡和线粒体功能障碍来选择性地杀死前列腺癌细胞. 这种传统的草药显示出治疗侵袭性前列腺癌的潜力,对正常细胞的伤害最小.

关键词:
阿特拉提洛德斯兰塞亚DC.灭症 (apoptosis) 是一种死亡的过程.潜在的线粒体膜潜力前列腺癌是前列腺癌.有活性氧物种的反应性氧物种.

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Drug disposition in the body is a complex process and can be studied using two major approaches: the model and the model-independent approaches.
The model approach uses mathematical models to describe changes in drug concentration over time. Pharmacokinetic models help characterize drug behavior in patients, predict drug concentration in the body fluids, calculate optimum dosage regimens, and evaluate the risk of toxicity. However, ensuring that the model fits the experimental data accurately...
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Model Approaches for Pharmacokinetic Data: Distributed Parameter Models

Pharmacokinetic models are mathematical constructs that represent and predict the time course of drug concentrations in the body, providing meaningful pharmacokinetic parameters. These models are categorized into compartment, physiological, and distributed parameter models.
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