术前维生素D值对全甲状腺切除术后低血症的影响
Manar Mahdi Qanbar1, Selen Soylu1, Serkan Teksöz1
1Department of General Surgery, Cerrahpaşa Faculty of Medicine, İstanbul University-Cerrahpaşa, İstanbul, Türkiye.
Turkish journal of surgery
|February 21, 2025
概括
手术前维生素D水平较低 (<10 ng/mL) 显著增加了甲状腺切除术后缺血的风险. 维持足够的维生素D对于手术后的调节至关重要.
科学领域:
- 内分泌学 在内分泌学.
- 手术瘤学手术瘤学
- 营养科学 营养科学
背景情况:
- 低血是甲状腺切除术后经常出现的并发症.
- 维生素D对于平衡和骨代谢至关重要.
研究的目的:
- 调查手术前维生素D水平与术后低血症发生率之间的关联.
- 为了确定在全甲状腺切除术后患低血症的风险较高的患者.
主要方法:
- 对899名接受全甲状腺切除术的患者进行了回顾性分析.
- 排除患有先前存在的疾病或补充剂的患者.
- 根据手术前的维生素D水平 (<10 ng/mL与≥10 ng/mL) 分为两组的分层.
主要成果:
- 与手术前维生素D水平≥10 ng/mL (11.2%和3.2%) 的患者相比,患有无症状 (17.1%) 和症状 (6.7%) 低血症的患者的比例更高.
- 患有低血症 (14.79 ng/mL) 的患者的平均手术前维生素D水平明显低于保持正常血症 (19.12 ng/mL) 的患者.
- 与男性相比,女性的维生素D水平较低.
结论:
- 手术前的维生素D缺乏 (<10 ng/mL) 是甲状腺切除术后出现低血症的重要危险因素.
- 在甲状腺手术前评估和优化维生素D状况可能有助于减轻术后低血症.
- 进一步的研究可以探索有针对性的维生素D补充策略.
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