预后营养指数和喘之间的关系:一个横截面分析
Zhimeng Jiang1,2, Xingyu Zhu1,3, Huixin Jiang4
1Graduate School of Hebei North University, Zhangjiakou, Hebei, China.
Frontiers in nutrition
|February 21, 2025
概括
更高的预后营养指数 (PNI) 水平与更低的喘患病率有关. 这表明营养状况可能在喘管理中发挥作用,因此需要进一步调查早期干预措施.
科学领域:
- 呼吸系统医学 呼吸系统医学
- 营养科学 营养科学
- 流行病学 流行病学
背景情况:
- 喘是一种慢性呼吸道炎症疾病.
- 营养状况和炎症与喘有关.
- 预后营养指数 (PNI) 和喘患病率之间的关系尚未得到充分证实.
研究的目的:
- 调查PNI和喘患病率之间的关联.
- 为了确定PNI指出的营养状况是否与喘相关.
主要方法:
- 利用了2017-2020年国家健康和营养检查调查 (NHANES) 的数据.
- 包括7,869名成年参与者,按PNI四分位数分类.
- 使用多变量回归和子组分析来评估PNI-喘相关性.
主要成果:
- 较高的PNI水平与较低的喘患病率显著相关.
- 每个单位的PNI增加与喘患病率减少3%相关 (OR0.97).
- 在PNI和喘之间观察到显著的负面趋势 (p=0.0041),在各个子组中一致.
结论:
- 较低的PNI值与喘患病率的增加有关.
- 低PNI个体的营养干预和炎症管理可以减少喘发病率和严重程度.
- 建议进行进一步的前性研究来证实这些发现.
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