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Updated: May 27, 2025

Lumped-Parameter and Finite Element Modeling of Heart Failure with Preserved Ejection Fraction

Lumped-Parameter and Finite Element Modeling of Heart Failure with Preserved Ejection Fraction

Published on: February 13, 2021

针对心力衰竭患者的表型分析和保存的喷射分数

Giovanni Battista Bonfioli¹, Matteo Pagnesi¹, Leonardo Calò²

¹Institute of Cardiology, ASST Spedali Civili di Brescia, Department of Medical and Surgical Specialties, Radiological Sciences and Public Health, University of Brescia, Piazzale Spedali Civili 1, 25123 Brescia, Italy.

European heart journal supplements : journal of the European Society of Cardiology

|February 21, 2025

概括

保持喷射分数 (HFpEF) 的心力衰竭正在上升,结果不佳. 本综述探讨了HFpEF表型及其治疗影响,以改善患者管理.

科学领域:

心脏病学心脏病学
内部医学内部医学

背景情况:

心力衰竭与保存的喷射分数 (HFpEF) 的患病率正在增加.
HFpEF带有不良预后,死亡率高,住院风险高.

研究的目的:

审查目前关于HFpEF表型分析的证据.
描述不同的HFpEF表型及其治疗影响.
讨论有关HFpEF差异诊断的临床情况.

主要方法:

对HFpEF表型鉴定研究的文献综述.
对不同HFpEF表型的证据综合.
基于已识别的表型的治疗策略的分析.

主要成果:

HFpEF表现出显著的临床异质性.
已经确定了几种不同的HFpEF表型.
现型特定的管理策略正在出现.

结论:

了解HFpEF表型对于个性化治疗至关重要.
根据特定的HFpEF概况量身定制治疗可能会改善患者的治疗结果.
需要对HFpEF异质性的进一步研究.

关键词:

伴随性疾病伴随性疾病 HFpEF HFpEF 的意思是什么现象类型现象类型进行个人资料制作.

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Pathophysiology of Heart Failure

Pathophysiology of Heart Failure

Heart failure (HF) is a progressive syndrome involving ventricles that leads to inadequate cardiac output. It can be classified based on location and output or ejection fraction. Ejection fraction (EF) is an essential measurement in the diagnosis and surveillance of HF. Reduced EF corresponds to systolic heart failure (HFrEF). However, HF with preserved ejection fraction (HFpEF) is becoming increasingly prevalent. Also known as diastolic HF, this form of HF is related to aging. The...