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Updated: Oct 13, 2026

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收缩:二氧化纳米颗粒在HepG2细胞中诱导线粒体相关的亡

Zhenglin Xia1, Jingliang He2, Bowei Li1

  • 1Department of General Surgery, Guangdong Second Provincial General Hospital, Southern Medical University Guangzhou 510515 People's Republic of China guoan_66@163.com.

RSC advances
|February 21, 2025
PubMed
概括

这篇文章已被撤回. 最初的研究,DOI 10.1039/C8RA05132A,不再被认为是有效的或科学记录的一部分.

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Electron Transport Chain: Complex I and II01:46

Electron Transport Chain: Complex I and II

The mitochondrial electron transport chain (ETC) is the main energy generation system in the eukaryotic cells. However, mitochondria also produce cytotoxic reactive oxygen species (ROS) due to the large electron flow during oxidative phosphorylation. While Complex I is one of the primary sources of superoxide radicals, ROS production by Complex II is uncommon and may only be observed in cancer cells with mutated complexes.
ROS generation is regulated and maintained at moderate levels necessary...