开发和验证一个深度学习增强的预测模型,用于肺栓塞的可能性
Yu Tian1,2, Jingjie Liu3, Shan Wu4
1Vascular Surgery Department, Shanxi Bethune Hospital, Shanxi Academy of Medical Sciences, Third Hospital of Shanxi Medical University, Tongji Shanxi Hospital, Taiyuan, China.
Frontiers in medicine
|February 21, 2025
概括
一个新的深度学习模型,PE-Mind,准确地预测深静脉血栓 (DVT) 患者的肺栓塞 (PE) 风险. 这种人工智能工具为有针对性的风险评估提供了更高的精度.
科学领域:
- 医疗信息学 医疗信息学
- 人工智能在医学中的应用
- 心血管医学 心血管医学
背景情况:
- 肺栓塞 (PE) 是死亡的一个重要原因.
- 对急性深静脉血栓塞 (DVT) 的准确风险分层对于患者管理至关重要.
- 目前用于PE风险评估的临床工具存在局限性.
研究的目的:
- 开发一个精确有效的深度学习模型,PE-Mind,用于预测PE风险.
- 克服当前临床风险评估工具的局限性.
- 为急性DVT患者提供更有针对性的风险评估解决方案.
主要方法:
- 分析了来自DVT患者的临床数据,选择了37个关键特征.
- 一个卷积神经网络 (CNN) 模型,PE-Mind,是用定制模块开发的.
- 该PE-Mind模型与五种已建立的预测模型进行了验证.
主要成果:
- 在前测试组中,PE-Mind的准确度为0.7826和AUC为0.8641.
- 与现有的预测模型相比,该模型显示出更高的准确性和可靠性.
- 为实时临床使用,开发了一个Web服务器PulmoRiskAI.
结论:
- PE-Mind模型提高了急性DVT患者PE风险评估的准确性和可靠性.
- 卷积架构和剩余模块显著提高了预测性能.
- PE-Mind为临床医生提供了一种有价值的工具,用于管理患有PE风险的DVT患者.
相关概念视频
Pulmonary Embolism I: Introduction
Pulmonary embolism (PE) occurs when a thrombus, fat or air embolus, amniotic fluid, or tumor tissue blocks one or more pulmonary arteries. These blockages originate in the venous system or the right side of the heart.EtiologyPE primarily arises from deep vein thrombosis (DVT) and other hypercoagulable states, such as inherited thrombophilias. Additional etiological factors include venous stasis, commonly seen in obesity, and endothelial injury from surgery and trauma. Less common causes include...
Pulmonary Embolism II: Diagnostic Studies and Interprofessional Care
Diagnosing Pulmonary EmbolismDiagnosing pulmonary embolism (PE) involves clinical assessment and advanced imaging tests. The preferred diagnostic tool is the spiral (helical) CT scan or CT angiography (CTA), which uses intravenous contrast media to visualize the pulmonary vasculature and identify emboli.A ventilation-perfusion (V/Q) scan is an alternative for patients unable to receive contrast media. This scan includes both perfusion and ventilation scanning. Perfusion scanning involves...
Pulmonary Embolism III: Nursing Management
A pulmonary embolism occurs when a thrombus, amniotic fluid, tumor tissue, fat, or air embolus blocks one or more pulmonary arteries. Effective nursing management and patient education are crucial for improving outcomes and preventing recurrence.Nursing management starts with obtaining a comprehensive patient history, particularly noting any history of deep vein thrombosis (DVT). Assess for clinical manifestations, including dyspnea, chest pain, crackles, heart murmurs, and signs of right-sided...
Pulmonary Embolism I: Introduction
A blood clot, or thrombus, is a semi-solid mass composed of fibrin, platelets, and red blood cells. When it forms within a vessel, it can obstruct blood flow, known as thrombosis. If part of the clot detaches, it becomes an embolus that can travel and block distant vessels. When this occurs in the pulmonary arteries, it causes a condition known as pulmonary embolism (PE).Origin and ImpactMost often, the embolus originates from a thrombus in the deep veins of the lower limbs, a condition called...


