肺癌患者在新辅助免疫治疗期间的创伤后生长和痛苦之间的纵向关系
Qiao Chu1, Fenghuan Sun2, Xinsheng Zhu2
1School of Public Health, Shanghai Jiao Tong University School of Medicine, No.227 South Chongqing Rd, Shanghai 200025, China.
International journal of clinical and health psychology : IJCHP
|February 21, 2025
概括
在接受新辅助免疫治疗的肺癌患者中,较低的情绪压力预测了随着时间的推移,创伤后生长 (PTG) 的增加. 年龄和教育等个人因素影响这种关系,建议量身定制的干预措施.
科学领域:
- 心理学 心理学 心理学
- 在瘤学瘤学.
- 医学社会学 医学社会学
背景情况:
- 创伤后生长 (PTG) 被认为可以增强癌症患者的福祉.
- 在接受新辅助治疗的患者中,PTG和情绪困扰之间的纵向相互作用尚未得到充分研究.
研究的目的:
- 调查困难 (抑郁,焦虑,负面影响) 和PTG之间的线性和二次纵向关联.
- 检查接受新辅助免疫治疗的肺癌患者之间这些纵向关系的个体变异.
主要方法:
- 分析了三项临床试验中231名肺癌患者的数据.
- 交叉滞后小组分析和多组结构方程建模被用于评估纵向关联和个体差异.
主要成果:
- 发现了显著的单向线性关系:较低的痛苦水平预测了随着时间的推移增加的PTG.
- 焦虑对PTG的影响在具有高等教育或较低财务负担的患者中更强.
- 负面影响对PTG的影响在老年患者中更为明显;没有观察到显著的二次效应.
结论:
- 在新辅助疗法期间,减少情绪焦虑似乎促进肺癌患者的创伤后生长.
- 痛苦对PTG的纵向影响因患者的特征如年龄,教育和财务状况而受到缓解.
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