释放低CpG传递体的潜力,用于优质的CAR-T细胞治疗

Jianyao Zeng1, Yan Sun1,2, Yuan Fang2

  • 1School of Medicine, Shanghai University, Shanghai, China.

Frontiers in immunology
|February 21, 2025
PubMed
概括

这项研究开发了一种低CpG的转体子,用于化学抗原受体 (CAR) T细胞治疗,增强抗瘤疗效和减少炎症. 新型LCG CAR-T细胞在临床前模型中显示出更好的安全性和有效性.

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