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氧化添加-减少消除在阿辛尼丁和斯蒂比尼丁中心的体-元素合作的支持下

Vít Kremláček¹, Erik Kertész², Milan Erben¹

¹Department of General and Inorganic Chemistry, FCHT, University of Pardubice, Studentská 573, Pardubice, 532 10, Czech Republic.

Chemistry (Weinheim an der Bergstrasse, Germany)

|February 21, 2025

概括

这项研究详细介绍了pnictinidenes与氧化,二二硫化,2-二和4--1,2,4-三-3,5-的反应,产生新的有机和有机化合物. 这项研究阐明了这些含有菌素的分子的反应机制和结构特征.

科学领域:

有机金属化学有机金属化学
无机化学无机化学有机化学
合成化学合成化学

背景情况:

普尼西丁是一种具有独特反应性的低价值主要组化合物的类.
了解菌素中心的反应性对于开发新的合成方法至关重要.
新型有机和有机反化合物的合成和表征具有显著的兴趣.

研究的目的:

为了研究pnictinidenes与各种电友反应剂的反应.
合成和描述新的有机和有机反化合物.
用实验和计算方法阐明反应机制.

主要方法:

合成的pnictinidenes [2-(RNHCH2)-6-(RN=CH) C6H3]E (E=As, Sb). 这种类型的化合物有:
与过氧化,二二硫化,2-二二和4--1,2,4-三-3,5-二的反应.
通过IR,拉曼,NMR光谱和单晶X射线衍射进行表征.
DFT计算用于研究反应机制.

主要成果:

新型化合物[2-[DippNCH2]-6-[DippN=CH]C6H3]E[O2CPh] (2As/Sb),[2-[DippNCH2]-6-[DippN=CH]C6H3]As[SPh] (3As),[2-[DippNHCH2]-6-[DippN=CH]C6H3]Sb[SPh]2 (3'Sb),[2-[DippNCH2]-6-[DippN=CH]C6H3]Sb[SPh] (3Sb),[2-[DippNCH2]-6-[DippN=CH]C6H3]Sb[SPh] (3Sb),[2-[DippNCH2]-6-[DippN=CH] (4As/Sb),[2-[DippNCH2]-6-[DippN=CH]-6-[SPh]-6-[SPh] (5As/Sb) ] (5Sb) 已经合成了这些化合物,这些化合物也包括在内.
在1Sb与二二硫化物反应中观察到动态平衡.
研究了热诱导的还原性消除和C-H激活.
DFT的计算支持了所提出的反应机制.

结论:

普尼提尼对各种电友具有多样性的反应性,使其能够合成新的有机和有机化合物.
反应途径包括氧化,联结体交换和C-H激活.
这项研究提供了对低价值基化合物的化学有价值的见解.

关键词:

它们是反的.亚是一种.氧化添加剂的添加剂.皮尼斯蒂尼丁化剂的使用减少性消除减少性消除

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