诊断到切除时间和心房的复发之间的相关性:系统性审查和元分析
Muhammad Arslan Ul Hassan1,2,3, Sana Mushtaq2,3, Tao Li1,2
1Department of Cardiology, General Hospital of Ningxia Medical University, Yinchuan, 750004, China.
概括
经过切除的心房动 (AF) 患者的诊断至切除时间 (DAT) 缩短与减少AF复发有关. 与较长的间隔相比,1年或更短的DAT显著降低了复发风险.
科学领域:
- 心脏病学 心脏病学
- 医学研究 医学研究
- 临床试验 临床试验
背景情况:
- 心房动 (AF) 的复发受诊断到消融时间 (DAT) 的影响,这是一个可修改的因素.
- 优化DAT可能会改善AF患者的切除结果.
研究的目的:
- 为了研究诊断到切除时间 (DAT) 和AF复发之间的关联.
- 为了确定AF诊断后除手术的最佳时间框架.
主要方法:
- 在PubMed,谷歌学者和Cochrane图书馆进行系统的文献搜索,截至2024年6月.
- 包括报告DAT和AF复发的观察性研究.
- 使用随机效应模型进行元分析,以比较DAT ≤1年与>1年.
主要成果:
- 包括6项观察性研究,共14862名参与者.
- DAT > 1年与增加AF复发风险有关.
- DAT ≤ 1 年与明显较低的AF复发相关 (RR,0.76;P < 0.01).
- DAT ≤3年也显示出与较低的AF复发的相关性 (RR,0.82;P <0.01).
结论:
- 有证据表明,最佳的AF除发生在诊断后1年内.
- 与较长的DAT相比,≤1年的DAT与AF复发减少了24%.
- 缩短DAT可能是改善AF患者长期结果的关键因素.
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