早期听觉处理对对精神分裂症认知疗法的负面症状反应的影响
Alice M Saperstein1, Ryan Brennan2, Min Qian3
1Department of Psychiatry, Columbia University Vagelos College of Physicians & Surgeons, and New York-Presbyterian, New York State Psychiatric Institute, New York, NY 10032, United States.
Schizophrenia bulletin
|February 21, 2025
概括
认知补救 (CR) 与早期听觉处理 (EAP) 培训显著改善了精神分裂症患者的负面症状. 没有缺陷的人没有从EAP培训中受益,突出了个性化治疗需求.
科学领域:
- 神经科学是一个神经科学.
- 精神病学是一个精神病学.
- 临床心理学 临床心理学
背景情况:
- 早期听觉处理 (EAP) 缺陷在精神分裂症谱系障碍中越来越被认可.
- 认知补救 (CR) 显示出减轻负面症状的希望,但需要个性化的方法.
- 将CR与EAP培训进行调整可能会优化治疗反应.
研究的目的:
- 根据基线EAP功能,调查认知补救 (CR) 中的早期听觉处理 (EAP) 培训是否对精神分裂症谱系障碍患者有差异性益处.
- 为了确定EAP培训是否增强了EAP缺陷的精神分裂症患者与完整EAP患者相比减少负面症状.
主要方法:
- 150名患有精神分裂症或精神分裂情绪障碍的门诊患者的EAP功能 (完好或损伤) 被评估.
- 参与者被随机分配到具有或没有EAP培训的CR.
- 负面症状使用正负综合征量表 (PANSS) 测量治疗后和3个月的随访.
主要成果:
- 认知补救 (CR) 显著改善了整体的负面症状.
- 只有EAP受损的参与者在EAP培训中显示出显著的负面症状减少.
- 没有接受EAP培训的EAP受损的参与者在负面症状的改善很小.
结论:
- 早期听觉处理 (EAP) 评估对于在精神分裂症谱系障碍中个性化认知补救 (CR) 是至关重要的.
- 在CR中的EAP培训为EAP受损个体的负面症状提供了显著的临床益处.
- 个性化CR,以EAP评估为基础,优化了认知和负面症状的治疗结果.
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