在加纳获得抗逆转录病毒疗法和艾滋病毒检测服务的客户中,艾滋病毒再检测的流行率
Raphael Adu-Gyamfi1, Stephen Ayisi Addo1, Nyonuku Akosua Baddoo2
1National AIDS/STI Control Programme, Ghana Health Service, Accra, Ghana.
PloS one
|February 21, 2025
概括
在加纳,高水平的艾滋病毒再检测在意识到自己的身份的人群中,使艾滋病毒阳性数字膨胀,并阻碍了与护理的联系. 解决再检测实践对于准确的艾滋病毒反应数据和实现国家目标至关重要.
科学领域:
- 公共卫生 公共卫生
- 流行病学 流行病学
- 艾滋病毒/艾滋病研究研究
背景情况:
- 加纳的目标是实现其艾滋病毒应对措施的95-95-95目标.
- 低关联与护理率可能会受到已经意识到自己艾滋病毒状况的个体中高反复检测率的影响.
- 重复测试可能导致对第一个95 (测试) 的高估和对第二个95 (与护理的联系) 的低估.
研究的目的:
- 确定在加纳艾滋病毒感染者 (PLHIV) 之间重新进行艾滋病毒检测的流行率,这些人知道自己的身份.
- 为了调查这一群体中HIV再检测背后的原因.
主要方法:
- 在加纳的三个生态区进行了基于设施的横截面研究.
- 来自30个ART中心和90个HTS中心的11,145人参加了.
- 使用分析工具收集数据,用于测试行为和与客户和卫生工作者进行焦点小组讨论.
主要成果:
- 在ART患者中重新测试的流行率为32.9%.
- 在那些检测阳性的人中,53.1%以前有艾滋病毒诊断.
- 重复检测的关键原因包括诊断的确认,怀疑,文档问题和宗教信仰.
结论:
- 六年来高的HIV再检测流行率显著影响了HIV阳性率和与护理的联系.
- 对重新测试实例的准确核算对于提高数据完整性至关重要.
- 针对重复测试的干预措施可以提高数据准确性,改善加纳与护理率的联系,帮助实现95-95-95目标的进展.
更多相关视频
23:56Comprehensive & Cost Effective Laboratory Monitoring of HIV/AIDS: an African Role Model
Published on: October 31, 2010
16.7K
13:58Amplifying and Quantifying HIV-1 RNA in HIV Infected Individuals with Viral Loads Below the Limit of Detection by Standard Clinical Assays
Published on: September 26, 2011
31.5K
相关概念视频
Retrovirus Life Cycles
45.6K
Retroviruses have a single-stranded RNA genome that undergoes a special form of replication. Once the retrovirus has entered the host cell, an enzyme called reverse transcriptase synthesizes double-stranded DNA from the retroviral RNA genome. This DNA copy of the genome is then integrated into the host’s genome inside the nucleus via an enzyme called integrase. Consequently, the retroviral genome is transcribed into RNA whenever the host’s genome is transcribed, allowing the...
45.6K
Sexually Transmitted Infections
258
Sexually transmitted infections (STIs) are diseases transmitted primarily through unsafe sexual interactions. Bacteria, viruses, or parasites cause them and can result in severe health complications if untreated.ChlamydiaThe bacterium Chlamydia trachomatis is responsible for the disease Chlamydia, the most common STI in the United States. This peculiar pathogen requires human cells to reproduce, residing intracellularly. The initial infection often goes unnoticed because it typically does not...
258
