对轻度认知障碍的老年人进行基于平板电脑和小组的多组分认知刺激:单组试点研究和随机对照试验协议
Khanitin Jornkokgoud1,2, Pattrawadee Makmee3, Peera Wongupparaj4
1College of Research Methodology and Cognitive Science, Burapha University, Chon Buri, Thailand.
JMIR research protocols
|February 21, 2025
概括
基于平板电脑的多组件认知刺激疗法 (MCST) 显著改善了轻度认知障碍 (MCI) 的老年人认知能力,并减少了抑郁和焦虑. 这种技术增强的干预措施对与MCI人群工作的心理健康专业人员来说是有前途的.
科学领域:
- 老年学是一门学科.
- 神经科学是一个神经科学.
- 精神病学是一个精神病学.
背景情况:
- 认知刺激疗法 (CST) 是一种针对痴呆症和轻度认知障碍 (MCI) 的小组干预,可以提高认知能力和生活质量.
- 以前的研究表明,将技术设备纳入小组干预可能会带来额外的好处.
研究的目的:
- 评估基于药片和小组的多组分认知刺激疗法 (MCST) 对改善MCI老年人的认知功能的有效性.
- 报告一项试验的协议,评估MCST计划对MCI患者的影响.
主要方法:
- 一项试点研究涉及30名患有MCI的个人,他们参加了10次基于平板电脑和小组的MCST.
- 随后的随机对照试验将比较基于平板电脑的MCST,基于平板电脑的CST以及来自半城市社区的93名患有MCI的个人中的对照组.
- 评估包括测试前和测试后的评估,包括基于计算机的神经心理测试和脑电图,以分析认知,行为和情绪影响.
主要成果:
- 试点研究表明,干预后认知能力显著改善 (P<.001),抑郁症减少 (P=.002),焦虑症减少 (P=.001).
- 生活质量没有显著变化 (P=.18).
- 随机对照试验正在进行中,数据分析已经开始,结果预计将在2025年中后期发布.
结论:
- 这项研究代表了中等收入国家中MCI老年人的第一个基于平板电脑组的MCST.
- 它旨在通过详细的数据分析阐明观察到的积极结果的神经心理基础.
- 这些发现将为为MCI人群实施MCST的心理健康专业人员提供宝贵的知识和指导.
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