1992年至2022年加拿大的特定年龄肺癌发病率趋势
Matthew T Warkentin1, Johnathan A Murray1, Yibing Ruan2
1Department of Oncology, Cumming School of Medicine, University of Calgary, Calgary, AB, Canada.
Cancer epidemiology
|February 21, 2025
概括
在加拿大,肺癌发病率在两性之间正在趋同. 虽然男性的发病率下降,但最近女性的发病率正在下降,年轻女性现在首次出现更高的发病率.
科学领域:
- 流行病学 流行病学
- 公共卫生 公共卫生
- 在瘤学瘤学.
背景情况:
- 从历史上看,男性的肺癌发病率高于女性.
- 最近的趋势显示,两性肺癌发病率的趋同.
- 这项研究考察了加拿大的特定年龄的肺癌发病率趋势.
研究的目的:
- 详述1992年至2022年加拿大的特定年龄的肺癌发病率趋势.
- 分析性别特异性和出生队列对肺癌发病率的影响.
- 了解加拿大的肺癌发展模式.
主要方法:
- 利用加拿大统计局 (1992-2022) 的肺癌发病率数据.
- 员工联结点回归计算发病率和年度百分比变化 (APC).
- 分析了使用发病率比率 (IRR) 和95%置信区间 (CI) 的出生队列效应.
主要成果:
- 35岁以上加拿大男性的肺癌发病率下降,特别是65岁以上的男性.
- 55岁以下的女性显示下降趋势;55岁以上的女性显示稳定/增长率至2017年.
- 1957年以后出生的男性的风险较低;女性的风险在1943-47年达到顶峰,然后下降.
- 这是第一次,年轻女性的肺癌发病率高于男性.
结论:
- 肺癌发病率的性别差异正在缩小.
- 几十年来,男性肺癌的发病率一直在下降;女性的下降是最近的.
- 现在年轻女性的肺癌发病率高于男性,这是一个新的趋势.
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