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Updated: Aug 1, 2026

Efficient Generation and Editing of Feeder-free IPSCs from Human Pancreatic Cells Using the CRISPR-Cas9 System
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Efficient Generation and Editing of Feeder-free IPSCs from Human Pancreatic Cells Using the CRISPR-Cas9 System

Published on: November 8, 2017

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一个高效的,非病毒阵列的CRISPR查平台,用于iPSC衍生的骨髓和小质模型

Sonja Meier1, Anne Sofie Gry Larsen2, Florian Wanke1

  • 1Pharma Research and Early Development, Neuroscience and Rare Diseases, F. Hoffmann-La Roche Ltd, 4070 Basel, Switzerland.

Stem cell reports
|February 21, 2025
PubMed
概括

研究人员使用CRISPR-Cas9基因编辑来研究人类微质中的脂质处理. 他们发现mTORC1通路对脂质储存至关重要,影响阿尔茨海默病和神经炎症研究.

关键词:
在这里,APOEOE是APOE.基因编辑CRISPR-Cas9基因编辑排列基因查 排列基因查由iPSC衍生的微质细胞.脂质的积累 脂质的积累脂质滴水屏幕 脂质滴水屏幕脂质新陈代谢 脂质新陈代谢脂质调节 脂质调节 脂质调节lysosome 溶解酶体是如何形成的在 mTORC1 的情况下,mTORC1 是

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相关概念视频

CRISPR01:59

CRISPR

Genome editing technologies allow scientists to modify an organism’s DNA via the addition, removal, or rearrangement of genetic material at specific genomic locations. These types of techniques could potentially be used to cure genetic disorders such as hemophilia and sickle cell anemia. One popular and widely used DNA-editing research tool that could lead to safe and effective cures for genetic disorders is the CRISPR-Cas9 system. CRISPR-Cas9 stands for Clustered Regularly Interspaced Short...